I would like to thank my supervisors, Professors Mark Good and Rob Honey, listed in purely alphabetical order as their intelligence, contributions, support and, where necessary, motivational talks were equal and without parallel.
I am also extremely grateful to Dr. Mihaela Iordanova, for basically showing me exactly what it was I was meant to be doing on countless occasions, and always being willing to lend assistance whenever required.
I must also thank my family for their support and patience, specifically my Mam and Dad, without whom I wouldn’t be here, or, in fact, anywhere. I would also like to thank Mum and Dad Sachdev, for their generosity and support, and tolerance of the bizarre individual who is now a part of the family.
Finally, I must thank my wonderful wife Vanita, as without her support (mental, motivational, and financial) I may never have completed this thesis.
This work was funded by a studentship from the BBSRC